CSF Specimens

In cytology, cerebrospinal fluids are most commonly evaluated to detect and characterize malignancy which may have gained access to the central nervous system. While in most individuals CSF specimens are relatively easy to obtain, in some individuals collection may require radiographic guidance. In addition, due to lack of nutrients in most of these fluids, cells may rapidly degenerate rendering morphologic evaluation less than optimal if adequate care is not taken.

Collection of Cerebrospinal Fluid

 

Indications:

Detection and characterization of malignant cells in the central nervous system
Specimen Required: Minimum of 0.5 mL cerebrospinal fluid
Supplies: Standard cerebrospinal fluid collection equipment. Clean, clear 10 mL collection container for CSF.
Collection Procedure: Using standard CSF collection procedures, collect a minimum 0.5 mL or more of CSF. In general, morphology of cells within the CSF fluid can be adequately maintained with prompt refrigeration for 24 hours. Submit the specimen along with the completed cytology request form.