Proven Diagnostics Test Catalog

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ACTIN IGG

Test code:
ACTIN
Specimen type:
Serum
Tube type / collection container:
Specimen collection notes:
Either serum separator tube (SST) or nonserum separator (plain) tube acceptable.
What to submit:
0.5 mL aliquot of serum; minimum 0.2 mL.
Patient preparation:
None.
 
Specimen Processing Instructions:
Allow to clot. Centrifuge and submit 0.5 mL aliquot of serum
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.
Specimen stability:
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.
 
Reference range:
Negative: <20 units; Weak positive: 20.0 - 30.0 units; Moderate to strong positive: >30.1 units.
Alert limits:
None.
Additional information:
None.
CPT code(s):
83516
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided are based on AMA guidelines and are for informational purposes only.
When performed:
Monday and Thursday
Test includes:
Negative: <20 units; Weak positive: 20.0 - 30.0 units; Moderate to strong positive: >30.1 units.
Methodology:
Enzyme-Linked Immunosorbent Assay (ELISA)
Synonyms:
ASMA, Anti-Smooth Muscle Antibody
Anti-SM Muscle AB
F-Actin
Clinical Significance:
The presence of antibodies to anti-mitochondrial, gp210 and sp100 when used in conjunction with clinical findings and other laboratory tests can aid in the diagnosis of primary biliary cirrhosis.